pentacosadiynoic+acid





Thuyen, David Thuyen, David>>> The starting material, 1,9-nonanediol found in signmaaldrich.com, was treated with HBr as a reagent and resulted in 1-Bromo-1-tetradecyne. One of the -OH groups was substituted with Br.The molecule was then treated with dihydropyran, the alkene in the ring broke to form a bond on to the oxygen of the 1-Bromo-1-tetradecyne, and Br acted as a leaving group with an alkyne come in its place. Then the molecule was reacted through Jones Oxidation to result in a carboxylic acid group on the end of the molecule. In the second to last step the molecule was treated to with alcohol and H-O-CH3. Finally in a Base and SuBr the two long chains were brought together and produced pentacosa-10,12-diynoic acid. References: [] [] Wade, L.G. //Organic Chemistry//. 7th. Prentice Hall, 2009. This looks like a workable synthesis. You just need to finish the description with references. Bruce Bondurant

Dionne Milan, Ashleybeth Martinez, Lanny Lantigua

This is a nice synthesis and description. You just need to add references and you are done. Bruce Bondurant
 * //__ Reference: Notes taken at class, and reference paper from shared files __//**